Phase 2Pattern hair loss

PP405

DraftReviewed by the HairLoss99 editorial team · checked 17 Oct 2026

Pelage announced positive Phase 2a results in June 2025 (78 men and women, 4 weeks of daily dosing, 12-week follow-up) and a $120M Series B (Oct 2025, co-led by ARCH Venture Partners and GV/Google Ventures) to fund Phase 3.

How it works

Topical small molecule designed to reactivate dormant hair follicle stem cells and push them into the growth (anagen) phase, a regenerative rather than hormone-blocking approach.

Developer
Pelage Pharmaceuticals
Stage
Phase 2a completed; Phase 3 planned to start 2026
Latest update
Jun 2025
Evidence so far
Company or news reports only

Results so far

Met primary safety/efficacy endpoints with no systemic absorption; 31% of men showed >20% increase in hair density, including new growth in previously bald areas (press-release figures).

What's next

Phase 3 studies planned to begin in 2026.

In India

No India-specific development identified.

Sources

What to do today: treatments in development aren't a reason to wait. Ask a dermatologist about the options that work now, such as minoxidil and, for men, finasteride.

Discussion

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